About UsNational Projects

LPixel is involved in an array of national projects. As an entrepreneurial venture from the University of Tokyo, we will bring our knowledge and expertise in advanced technology to the following projects to promote the development of scientific innovation in our society.

The ImPACT program “Planned Serendipity” is one of LPixel’s past projects.

Project: Pathology Diagnosis Support System that uses Artificial Intelligence and Three-Dimensional Structure Information of Living Tissues

Strategic Core Technology Advancement ProgramMinistry of Economy, Trade and Industry

LPixel was selected to take part in the Strategic Core Technology Advancement Program, a project led by the Ministry of Economy, Trade and Industry. Together with TCK Co., Ltd., LPixel is developing a system that utilizes laser ablation technology that will rapidly conduct a three-dimensional structural analysis of living tissues at nano-resolution.

About the Project

As we start to see advancements in pathological diagnosis and reconstructive medicine, we can obtain more images that can be used for diagnosing patients. This has been brought to the attention in the medical field, as pathologists, who are already expected to possess a high level of skill to conduct the diagnosis, are confronted with an increasing volume of images for the diagnosis process. This is increasing the workload of the 2300 pathologists working in Japan, which constitutes less than 1% of all doctors working in the country.

We are developing a system that enables the observation of living tissues down to the nano level. The system, which primarily consists of an electron microscope, a laser ablation system, and a 3D image construction engine, is designed to minimize the damages associated with tissue imaging, acquire a large amount of slice images in short period of time, and generate a 3D image based on the slice images. By integrating deep learning technology, we aim to create a powerful tool that will facilitate pathologists with the diagnosis process.

We will utilize our knowledge and expertise in bio-medical imaging to develop the 3D image construction engine. With the seamless integration of the laser ablation system and an imaging instrument, this system is anticipated to both standardize and greatly enhance the efficiency of the pathological diagnosis process.

This system is slated for launch in 2018. Our objective is to provide powerful imaging solutions that meet the needs of clients around the world. In efforts to contribute to the advancements in medical diagnosis, we will continue to collaborate with our partners to bring a new era to medical imaging.

About the Strategic Core Technology Advancement Program

This organization, led by the Ministry of Economy, Trade and Industry, was founded to support the research and development of improving 12 specific kinds of manufacturing technology, such as precision processing and biotechnology.

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Project: Constructing models to Confer Environmental Robustness by Developing Multi-omics Technology of Polyploid Species

About Core Research for Evolutionary Science and Technology (CREST)Japan Science and Technology Agency

LPixel, together with Kihara Institute for Biological Research, National Institute of Advanced Industrial Science and Technology (AIST) and the University of Zurich, was selected to participate in CREST, a funding program by Japan Science and Technology Agency (JST). Our project is focused on constructing models to confer environmental robustness by developing multi-omics technology of polyploid species.

About the Project

The rapid global climate change is giving rise to an urgent need to breed crops that possess environmental robustness, or the adaptability to withstand extreme weather conditions such as low and high temperatures and varying degrees of humidity.

Through extensive research, it has been revealed that polyploids possess properties for environmental robustness. Staple crops such as wheat, cotton, coleseed, and arabica coffee are known to be polyploid. With its long history in Japanese agriculture, it is predicted that humans may have coincidentally taken advantage of the environmental robustness of such species. However, very little is researched in terms of omics technologies, and the molecular basis for environmental robustness is still not clearly understood.

This project will apply information science on omic technology to study polyploid species. The research will create a parent strain that can serve as a generalist that grows and prospers under diverse environmental conditions. The outcome of this project will make a significant contribution towards delivering a stable food supply to Japanese agriculture.

In this project, we will utilize our phenome analysis technology that can automatically, quantitatively, and continuously monitor the growth of the species through its shape, color, size and height. Scientists from Kihara Institute for Biological Research, Center for Ecological Research and the University of Zurich will be responsible for field data collection and conducting the necessary procedures to validate experimental data. The phenome data extracted from this step will be passed over to the research team in AIST Group, where they will be in charge of bioinformatics and conduct modeling based on DNA, meteorological data, and phenome data.

About JST CREST

JST CREST encourages researches that trigger the reformation of social and economic structures.

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Project: Planned Serendipity

Impulsing Paradigm Change through Disruptive Technologies (ImPACT)Cabinet Office

LPixel was selected to partake in the ImPACT program “Planned Serendipity,” a project funded by Japan’s Cabinet Office

About Planned Serendipity

This program, led by Keisuke Goda who currently works as a professor at the University of Tokyo, is focused on the development of the Serendipiter, cell searching technology that will quickly and precisely extract and analyze cells in a cell population, and find single target cells on a repeated basis. In life science research, serendipitous events are often described as finding a needle from a haystack. This project aims to change these serendipitous occurrences into planned occurrences that can lead to new discoveries on a controlled basis. We are involved in Project 4 of this program.


* Image taken from the ImPACT program “Planned Serendipity”

About ImPACT

The ImPACT program was established to create innovative scientific and technological innovations that will revolutionize various industries and our society as a whole.

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