LPixel is a startup founded by members from the University of Tokyo specializing in image analysis software and systems for life science research. We have integrated our expertise and experience in image analysis technology to facilitate researchers in the life sciences field.
Cytology: Light, fluorescence and electron microscopic images of plant and animal cells and tissues
Cytoskeletal system simulations
Genetics and bioinformatics, automated database search for genomic/transcriptomic sequences
Chemical screenings, lead chemical evaluations and toxicity assessments
Agriculture, Agricultural Sciences and Plant Factories
Quantification of disease resistance and morphological traits such as leaves, stems and roots using cameras and scanner images
Brain and Behavioral Science
Research for Alzheimer’s disease, neurotransmission, mouse tracking and changes in body surface temperature
Analysis of scanning electron microscopic images of alloy materials
Analysis of cerebral aneurysms and pathological images, classification of tumor cells
Analysis of three-dimensional shape of cells
3D reconstruction, intensity distribution analysis, visualization, quantification of volume and surface area
Mikami H, Harmon J, Kobayashi H, Hamad S, Wang Y, Iwata O, Suzuki K, Ito T, Aisaka Y, Kutsuna N, Nagasawa K, Watarai H, Ozeki Y, Goda K. (2018) Ultrafast confocal fluorescence microscopy beyond the fluorescence lifetime limit. Optica 5 (2): 117-126.
Norihiko S, Toshiyuki I, Fumio H, Masaki M, Hiroki K, Yoko M, Tomio A, Naoshi I, Junko A, Kaiyo T, Masashi T. (2018) Stemness and anti-cancer drug resistance in ABCG2 highly expressed pancreatic cancer is induced on 3D-culture condition. Cancer Science DOI: 10.1111/cas.13533
Ishii Y, Maruyama S, Fujimura-Kamada K, Kutsuna N, Takahashi S, Kawata M, Minagawa J (2018) Isolation of uracil auxotroph mutants of coral symbiont alga for symbiosis studies.
Scientific Reports DOI: 10.1038/s41598-018-21499-3
Soga K, Yamazaki C, Kamada M, Tanigawa N, Kasahara H, Yano S, Kojo Kei H, Kutsuna N, Kato T, Hashimoto T, Kotake T, Wakabayashi K, Hoson T (2017) Modification of growth anisotropy and cortical microtubule dynamics in Arabidopsis hypocotyls grown under microgravity conditions in space. Phyiol Plant. DOI: 10.1111/ppl.12640
Jiang Y, Lei C, Yasumoto A, Kobayashi H, Aisaka Y, Ito T, Guo B, Nitta N, Kutsuna N, Ozeki Y, Nakagawa A, Yatomi Y, Goda K (2017) Label-free detection of aggregated platelets in blood by machine-learning-aided optofluidic time-stretch microscopy. Lab on a Chip 17: 2426-2434.
Iwayama K, Aisaka Y, Kutsuna N, Nagano AJ (2017) FIT: statistical modeling tool for transcriptome dynamics under fluctuating field conditions. Bioinformatics. 33: 1672-1680.
Higaki T, Takigawa-Imamura H, Akita K, Kutsuna N, Kobayashi R, Hasezawa S, Miura T (2017) Exogenous cellulase switches cell interdigitation to cell elongation in a RIC1-dependent manner in Arabidopsis thaliana cotyledon pavement cells. Plant Cell Physiology 58(1): 106-119.
Akita K, Kobayashi M, Sato M, Kutsuna N, Ueda T, Toyooka K, Nagata N, Hasezawa S, Higaki T (2017) Cell wall accumulation of fluorescent proteins derived from a trans-Golgi cisternal membrane marker and paramural bodies in interdigitated Arabidopsis leaf epidermal cells. Protoplasma 254: 367-377.
Nagata K, Hashimoto C, Watanabe-Asaka T, Itoh K, Yasuda T, Ohta K, Oonishi H, Igarashi K, Suzuki M, Funayama T, Kobayashi Y, Nishimaki T, Katsumura T, Oota H, Ogawa M, Oga A, Ikemoto K, Itoh H, Kutsuna N, Oda S, Mitani H (2016) In vivo 3D analysis of systemic effects after local heavy-ion beam irradiation in an animal model. Scientific Reports 6: 28691.
Shimahara Y, Kutsuna N (2016) Detection of image manipulation and plagiarism in life science research. Editorial Office News (The official publication of the International Society of Managing and Technical Editors) 9: 16-19
Higaki T, Kutsuna N, Akita K, Takigawa-Imamura H, Yoshimura K, Miura T (2016) A theoretical model of jigsaw-puzzle pattern formation by plant leaf epidermal cells. PLOS Computational Biology 12(4): e1004833.
Nagashima T, Oami E, Kutsuna N, Ishiura S, Suo S (2016) Dopamine regulates body size in Caenorhabditis elegans. Dev Biol. 412: 128-138.
朽名夏麿 (2015) バイオイメージング分野における画像の自動分類. Medical Imaging Technology 33: 105-111.
Takahashi S, Kojo KH, Kutsuna N, Endo M, Toki S, Isoda H, Hasezawa S (2015) Differential responses to high- and low-dose ultraviolet-B stress in tobacco Bright Yellow-2 cells. Frontiers in Plant Science 6: 254.
Fujiwara T, Kawachi M, Sato Y, Mori H, Kutsuna N, Hasezawa S, Maeshima M (2015) A high molecular mass zinc transporter MTP12 forms a functional heteromeric complex with MTP5 in the Golgi in Arabidopsis thaliana. FEBS J 282: 1965-1979.
Akita K, Higaki T, Kutsuna N, Hasezawa S (2015) Quantitative analysis of microtubule orientation in interdigitated leaf pavement cells. Plant Signal Behav 10: e1024396.
Higaki T, Kutsuna N, Akita K, Sato M, Sawaki F, Kobayashi M, Nagata N, Toyooka K, Hasezawa S (2015) Semi-automatic organelle delection on transmission electon microscopic images. Sci Rep 5: 7794.
Kamba Shunsuke, Horiuchi Hideka, Oh Kouki, Fukuda Akihiro, Aya Tonouchi, Kutsuna Natsumaro, Sumiyama Kazuki (2018) The Detection and Differential Diagnosis of Colonic Lesions with an Artificial Intelligence Algorithm. Digestive Disease Week (DDW) 2018
Maruyama S, Ishii Y, Fujimura-Kamada K, Kutsuna N, Takahashi S, Makino T, Minagawa J, Kawata M (2018) Evolution of exon-intron boundary recognition in coral symbiotic algae. The Society for Molecular Biology & Evolution 2018
Daiju Ueda, Akira Yamamoto, Masataka Nishimori, Taro Shimono, Satoshi Doishita, Akitoshi Shimazaki, Shinichi Tsutsumi, Shinya Fukumoto, Choppin Antoine, Yuki Shimahara, Yukio Miki (2018) Development and Validation of Deep Learning Algorithms for Detecting Cerebral Aneurysms in MR angiography. The 77th Annual Meeting of the Japan Radiological Society
Miura T, Higaki T, Akita K, Kutsuna N, Takigawa-Imamura H (2016) Mechanism of jigsaw-puzzle pattern formation in plant leaf epidermal cell: modeling single cell shape by interface equation and convolution kernel. The 2016 (26th) annual meeting of the Japanese Society for Mathematical Biology
Kiminori Toyooka, Mayuko Sato, Mayumi Wakazaki, Kei Hashimoto, Megumi Kobayashi, Fumie Sawaki, Natsumaro Kutsuna, Noriko Nagata (2015) Construction of an Arabidopsis electron microscopy atlas. International Conference on Aabidopsis Research (ICAR)
Naoki Takata, Toru Taniguchi, Natsumaro Kutsuna (2015) Screening for regulatory factors that control a microtubule structure in hybrid aspen. Tree Biotechnology Conference 2015
Nagata N, Kato A, Sawaki F, Kobayashi M, Sato M, Higaki T, Kutsuna N, Hasezawa S, Myouga F, Toyooka K (2014) Challenge to organellomics by the transmission electron microscopy.The 2nd International Symposium on Plant Environmental Sensing